Tissue Repair Studies
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BPC-157 is a synthetic peptide, 15 amino acids long. It copies part of a larger protein found in human stomach fluid. Research in animal models has measured new blood vessel growth, how tendon cells move and spread, and how tissue repairs after injury. It holds up in stomach acid better than most peptides, which is unusual and has been studied on its own.
Synthetic pentadecapeptide (15 amino acids)
The pathways BPC-157 acts on — and what each one does. Signalling pathways studied in preclinical models · illustrative.
BPC-157 upregulates vascular endothelial growth factor (VEGF) expression, promoting new blood vessel formation and enhancing blood supply to injured tissue in preclinical models.
Research demonstrates BPC-157 enhances growth hormone receptor expression in tendon fibroblasts by 7× within 3 days, supporting tissue repair signaling cascades.
BPC-157 demonstrates broad cytoprotective properties across multiple organ systems in animal studies, with particular relevance to gastrointestinal and musculoskeletal tissues.
The main areas BPC-157 is being studied for — and the study-reported figures behind them.
Accelerated healing of Achilles tendon, MCL, and rotator cuff injuries in rat models with improved collagen fiber organization.
Chang et al. 2014
Cytoprotective effects against NSAID-induced damage, alcohol lesions, and inflammatory bowel disease models.
Sikiric et al. 2011
Demonstrated neuroprotective effects in traumatic brain injury and peripheral nerve damage models with improved recovery markers.
Sikiric et al. 2016
Promotes angiogenesis and accelerates blood vessel healing after surgical transection in animal models via NO system modulation.
Sikiric et al. 2019
Representative figures from published research. Bars fill as you scroll.
Figures are representative of published research findings and shown for reference.
Every batch of BPC-157 is sent to an accredited independent laboratory before it ships. Here is what we screen for.
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
|---|---|
| Molecular Weight | 1419.53 Da |
| Molecular Formula | C₆₂H₉₈N₁₆O₂₂ |
| Form | Lyophilized powder (5mg) |
| Purity | ≥99% (HPLC verified) |
| Testing | Third-party HPLC, Mass Spec, Endotoxin |
| Storage | -20°C for long-term stability |
| Solubility | Water-soluble |
| COA | Included with every order |
BPC-157 (Body Protection Compound-157) is a synthetic 15-amino acid peptide derived from a larger protein found in human gastric juice. It was discovered during research at the University of Zagreb, Croatia, and has been studied extensively in animal models for its tissue-protective and regenerative properties.
No. BPC-157 is not approved by the FDA or any regulatory agency for human use. It is classified as an unapproved drug. The FDA has issued warnings about BPC-157 being found in compounded products and dietary supplements. Only one Phase I clinical trial has been registered, and no Phase 2 or 3 trials have been completed.
Preclinical research (animal studies) has shown BPC-157 may accelerate healing of tendons, ligaments, muscles, and bones; protect the gastrointestinal tract from ulcers and inflammation; have neuroprotective effects in brain injury models; and promote blood vessel formation. All findings are from animal studies — no human clinical data exists.
BPC-157 has been studied in rodent models and in cultured cell systems, where published protocols examine tissue-repair and gastrointestinal endpoints. Study design, concentrations and endpoints differ between publications — consult the primary literature for the parameters used in each experiment.
No lethal dose was reached in preclinical toxicology studies, and no significant adverse effects have been reported in published research. However, BPC-157 has never completed human clinical trials, so its safety profile in humans is unknown. It should only be used for in vitro laboratory research.
Lyophilized (powder) form should be stored at -20°C for long-term stability, protected from light and moisture. BPC-157 is notably stable — it resists hydrolysis, enzymatic degradation, and gastric acid.
Independent published research indexed from PubMed and peer-reviewed journals — not Zorva Lab claims.
For Research Use Only.
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
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